Ri Han

Ph.D. Candidate · Computational Drug Design · Chem/Bioinformatics Lab, Chung‑Ang University
hanri@hanri.net hanri@cau.ac.kr ORCID Scholar GitHub

Summary

I am a Ph.D. candidate in computational drug design focusing on virtual screening, free energy perturbation (FEP), and molecular dynamics (MD) for receptor–ligand interaction studies. I build data‑ and physics‑based pipelines that connect bio/cheminformatics with molecular modeling to support precise lead optimization.

Research Interests

  • Purinergic receptor sequence–structure analysis
  • Virtual screening
  • Small‑molecule docking
  • Free energy perturbation (FEP) calculation
  • Molecular dynamics (MD) simulation

Affiliation

Chung‑Ang University · Chem/Bioinformatics Lab Lab site

Graduate student (Ph.D. program), Division of Chem/Bioinformatics

Education

Ph.D. in Global Innovative Drugs — Chung‑Ang University

Mar 2023 – Present · Division of Chem/Bioinformatics (Advisor: Prof. Yoonji Lee)

M.S. in Pharmacy — Chung‑Ang University

Mar 2021 – Feb 2023 · Division of Chem/Bioinformatics (Advisor: Prof. Yoonji Lee)

B.S. in Life Sciences — Daejin University

Mar 2009 – Feb 2013 · Department of Life Sciences

Publications

2025

MetaboGNN: predicting liver metabolic stability with graph neural networks and cross-species data J Cheminform (2025) 17:140
Park JH†, Han R†, Jang J†, Kim J†, Paik J*, Heo J*, Lee Y*
Read paper DOI: 10.1186/s13321-025-01089-y

2023

Revolutionizing Medicinal Chemistry: The Application of AI in Early Drug Discovery Pharmaceuticals (2023) 16(9):1259
R Han†, H Yoon†, G Kim, H Lee, Y Lee*
Read paper DOI: 10.3390/ph16091259
Identification of a Non‑Nucleoside Reverse Transcriptase Inhibitor against HIV‑1 ACS Infect Dis (2023) 9(8):1582–1592
Kim MJ, Yu KL, Han R, Lee Y, Oh K, You JC
Read paper DOI: 10.1021/acsinfecdis.3c00166
Systematic analyses of sequence conservation and ligand interactions of purinergic P1 and P2Y receptors Comput Struct Biotechnol J (2023) 21:889–898
Han R, Yoon H, Yoo J*, Lee Y*
Read paper DOI: 10.1016/j.csbj.2023.01.010

Awards

  • 2025 — Best Poster Award (2nd Class) (Asia Hub for e-Drug Discovery Symposium 2025)
  • 2024 — PSK Travel Award (Fall International Convention of The Pharmaceutical Society of Korea)
  • 2023 — New Drug Development AI Competition, Grand Prize (Ministry of Science and ICT)
  • 2023 — Best Poster Presentation Award, 14th AIMECS (AFMC International Medicinal Chemistry Symposium), Seoul

Grants

  • 2023–2024 — CAU Graduate Research Scholarship (GRS)

Extracurricular